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  3. CUB-X - Tablet inspection
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CUB-X - Tablet inspection
NIR-source-1-762x1024.webp
QC-tester1.webp
  1. CUB-X - Tablet inspection
  2. NIR-source-1-762x1024.webp
  3. QC-tester1.webp
  4. youtube - [Video]

CUB-X - Tablet inspection

For OSD development and commercial production


The CUB-X is an innovative and versatile tablet inspection system, which can be used for OSD product & process development, as well as for IPC sample analysis and full batch inspection & sorting.

It is equipped with novel spectroscopy and laser technologies allowing for high-speed highly accurate non-destructive measurement of tablet thickness, API’s mass fraction and moisture content.


Key benefits

  • Delivers accurate and reliable PAT data to enable rapid, data-driven real-time decisions (RTD).
  • Ensures strong data integrity and regulatory compliance
  • Supports the pathway toward Real-Time Release (RTR)
  • Scales seamlessly from R&D, Pilot phases and Tech-Transfer to full Commercial Manufacturing
  • Provides fully automated IPC monitoring, 24/7, year-round. Cheaper operations through automation
  • Strengthens Quality Control through continuous and consistent measurements
  • Versatile platform & technology-agnostic meeting all Control strategy requirements
  • Minimizes material waste with non-destructive, in-process testing
0.00 € 0.00 €

  • Maximum inspection speed
  • Maximum sampling rate
  • Minimum product width
  • Maximum product width
  • Minimum product height
  • Maximum product height
  • Measurement Accuracy
  • Weighing accuracy
  • Measurement Accuracy
  • Measurement Accuracy
  • Air extraction
  • Requested Compressed Air
  • Noise Level
  • Power Supply
  • Frequency
  • Non-Metallic Contact Parts
  • Product type
  • Function
  • Containment Level
  • Application Area
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Documents
CUB-X - Brochure.pdf

Real-time analysis


The CUB-X delivers high-speed, non-destructive analysis of tablets using NIR-SRS spectroscopy, capable of measuring API mass fraction and moisture content on up to 20,000 tablets per hour. At the same time, tablets can be automatically sampled at speeds of up to 400 tablets per hour for detailed measurements of mass, thickness, diameter or length, and hardness.

This powerful combination allows manufacturers to analyze each tablet for API content, while sampled units are evaluated for dosage accuracy, porosity, and content uniformity. The result is complete process control and consistent product quality.

CUB-X reporting

Embedded technologies

NIR-SRS spectroscopy


High-speed 4P tablet testing



High-precision tablet laser profiler

A laser line-scanning sensor profiles each tablet, while passing under the sensor, measuring its thickness with a precision of 50 µm. The tablet laser profiler also verifies the correct position and orientation of the tablet on the conveyor belt before it passes under the NIR-SRS sensor.

Each tablet is inspected by the multipoint NIR-SRS (Near-Infra-Red Spatially Resolved Spectroscopy) probe at a high frame rate, allowing multiple spectral acquisitions per tablet. An accurate prediction of one or multiple ingredients’ mass fraction – including water – is then done by chemometric modelling. The SRS technology allows to cover a larger tablet surface and a deeper measurement penetration compared to single-point NIR reflection techniques, resulting in more accurate prediction of the CQA’s. 

Samples can be sent to an embedded 4-parameter tablet tester at a rate of up to 400 tablets/h, measuring tablet mass, thickness, diameter/length, and hardness. The high sampling rate is achieved thanks to a purpose-designed sampling gate, which feeds tablets one by one directly to the measurement instruments

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Specifications

Capacity
Maximum inspection speed 20.000 tablets/h
Maximum sampling rate 400 tablets/h
Minimum product width 4 mm
Maximum product width 24 mm
Minimum product height 3 mm
Maximum product height 10 mm
Utilities
Air extraction Integrated Hepa filter H13
Requested Compressed Air Min 500 L/min - Min. 6 bar
Power Supply 380 V 3ph + N + PE
Frequency 50 Hz / 60 Hz
Environment
Noise Level <70 dB (A)
Containment Level Dust Tight
Material
Non-Metallic Contact Parts FDA approved
Application
Product type Tablet
Function Quality control
Application Area R&D
Weight Measurement
Weighing accuracy ± 1 mg in stable environment
Length Measurement
Measurement Accuracy ± 0,1 mm
Thickness Measurement
Measurement Accuracy ± 0,05 mm
Hardness Measurement
Measurement Accuracy ± 2 N (4-400 N range)

Frequently asked questions


Pharma Technology designs and manufactures advanced process equipment for solid dose pharmaceutical production, including tablet dedusters, capsule polishers, metal detection systems, in-process control solutions, and sorting equipment. All our machines are developed to support high efficiency, accuracy, and compliance with international quality standards.  

Yes. Most of our solutions are modular and available in different heights, containment levels, and with several options. Our team can help you configure the right setup for your specific throughput, space, or regulatory requirements.

We provide full life-cycle support: installation and commissioning, on-site training, preventive maintenance, spare parts, and remote troubleshooting. Our global service network ensures that your equipment remains reliable and compliant throughout its operating life.

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